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现在位置不用本金就能赚钱的方法>技术资料不用本金就能赚钱的方法>行业动态>新品动态>PacBio推出PacBio RS II基因测序仪

PacBio推出PacBio RS II基因测序仪

Pacific Biosciences2013年4月12日 16:29 点击:3125

美国Pacific Biosciences
 PacBio RS II Sequencing System

不用本金就能赚钱的方法 2013NIAN4YUE11RI Pacific BiosciencesGONGSIXUANBUTUICHUXINBANBENDEPacBioCEXUYI:PacBio RS II。ZHEIKUANXINDEDANFENZISHISHI(SMRT)DNACEXUXITONGNENGDAILAIXINGYEZUIGAODEYIZHIZHUNQUEXINGHEZUIZHANGDEDUZHANG,QIETONGLIANGJIAOZHIQIANDEBANBENZENGJIAYIBEI。

基于革命性的SMRT测序技术,PacBio RS II的平均读长达5,000 bp,最长读长超过20,000 bp。此系统提供了简单快速、端对端的SMRT测序流程,适合传染病、微生物、农业和复杂遗传病的研究。它让科学家能够快速经济地完成基因组组装、揭示并了解表观基因组,以及鉴定基因组变异。

有了PacBio RS II,可同时观察的测序反应数量增加一倍,这有效提高了系统通量。读取数量的增加将推动新的应用,如全长cDNA分析和全长16S宏基因组学。PacBio RS II特有PacBio的C2和XL试剂,自动de novo组装的新型分析软件,以及过去两年发布的其他改进,包括:一致准确性提高到>99.999%(Q50),平均读长增加4倍,以及DNA起始量降低10倍。

该仪器特有高性能的光学系统、自动化的液体处理以及环境控制中心,这一切都可以通过直观的触摸屏来管理。同时,它还包含了负责初步数据分析的计算之脑(computational brain),也称为刀片中心。这可以通过试剂和软件的改进,实现性能提升的无缝整合。

PacBio公司市场开发部的高级副总裁Kevin Corcoran表示:“除了在非常稳定的系统上提供更多高质量的数据,PacBio RS II还包括了2011年PacBio RS发布以来的所有性能改进。准确性、可靠性和通量的综合改进,以及成本效率提高,是许多研究人员一直梦寐以求的。”

Richard Gibbs博士是贝勒医学院人类基因组测序中心的主管,也是PacBio RS的早期用户之一。他谈道:“我一直对Pacific Biosciences利用这种独特技术实现的进展印象深刻。随着各项性能升级,我们处理更复杂项目的能力增加。我们目前正在使用这一系统来改进哺乳动物基因组的序列。”

现有PacBio RS系统的客户可购买升级包,将原有系统转化成最新的PacBio RS II。而新系统的安装有望在2013年第二季度开始。

April 11, 2013

Photo Release -- Pacific Biosciences Launches the PacBio(R) RS II Sequencing System

The Gold Standard in High-Accuracy Genome Finishing Expands Into New Applications

 

 

MENLO PARK, Calif., April 11, 2013 (GLOBE NEWSWIRE) -- Pacific Biosciences of California, Inc. (Nasdaq:PACB) today announced the launch of the PacBio® RS II — a new Single Molecule, Real-Time (SMRT®) DNA Sequencing System that provides the industry's highest consensus accuracy and longest read lengths, with double the throughput from the previous version of the system.

  The PacBio RS II System offers a simple, fast, end-to-end workflow for SMRT Sequencing in research areas including infectious disease and microbiology, agriculture, and complex genetic diseases with repeat expansions.


 

不用本金就能赚钱的方法A photo accompanying this release is available at

The PacBio RS II allows scientists to rapidly and cost effectively generate finished genome assemblies, reveal and understand epigenomes, and characterize genomic variation. Based on the company's revolutionary SMRT Sequencing technology, the RS II can generate average read lengths of 5,000 base pairs, with the longest reads above 20,000 base pairs in length. The PacBio RS II System, including consumables and software, provides a simple, fast, end-to-end workflow for SMRT Sequencing in research areas including infectious disease and microbiology, agriculture, and complex genetic diseases with repeat expansions.

With the PacBio RS II, the number of simultaneously observable sequencing reactions is doubled, which effectively doubles the throughput of the system. This increase in the number of reads will drive new applications such as full-length cDNA analysis and full-length 16S metagenomics. The PacBio RS II features PacBio's  and , new analysis software with automated de novo 不用本金就能赚钱的方法assembly, and other improvements released in the past two years, including: increased consensus accuracy to greater than 99.999% (Q50), a quadrupling of average read lengths, and a 10-fold reduction in input DNA required.

"In addition to providing more, high-quality data in a highly robust system, the PacBio RS II includes all of the performance improvements we have made since we launched the commercial PacBio RS System in 2011," said  Kevin Corcoran, Senior Vice President of Market Development. "The combined improvements in accuracy, reliability, and throughput, as well as increased cost efficiencies, are what many researchers have been waiting for in order to adopt SMRT Sequencing in their laboratories."

Richard Gibbs, Ph.D., Professor and Chair of the Department of Molecular and Human Genetics at Baylor College of Medicine and Director of the Human Genome Sequencing Center, was among the early access users of the PacBio RS不用本金就能赚钱的方法. "I have been very impressed with the progress Pacific Biosciences has made with this unique technology. With each performance upgrade, our ability to handle more complex projects increases. We are now using the system to improve the sequence of mammalian genomes."

Customers with existing PacBio RS Systems can purchase an upgrade, which will convert the PacBio RS to the new PacBio RS II. Installations of the new PacBio RS II System are expected to begin in the second quarter of 2013. For more information please visit .

About Pacific Biosciences

Pacific Biosciences of California, Inc. (Nasdaq:PACB) offers the PacBio® RS II Sequencing System to help scientists solve genetically complex problems. Based on its novel Single Molecule, Real-Time (SMRT®) Sequencing technology, the company's products enable: targeted sequencing to more comprehensively characterize genetic variations; de novo genome assembly to more fully identify, annotate and decipher genomic structures; and DNA base modification identification to help characterize epigenetic regulation and DNA damage. By providing access to information that was previously inaccessible, Pacific Biosciences enables scientists to increase their understanding of biological systems.

不用本金就能赚钱的方法The photo is also available via AP PhotoExpress.

CONTACT: Media:

         Maurissa Messier

         For Pacific Biosciences

         760.539.7417

         maurissa@bioscribe.com



         Investors:

         Trevin Rard

         Pacific Biosciences

         650.521.8450

         ir@pacificbiosciences.com

Source: Pacific Biosciences of California, Inc.

(来源: Pacific Biosciences )


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